Ku Tokyo amadziwika kuti Shinto Teito mchaka cha 2020, Minato Sahashi wazaka 19 ndiwanzeru kwambiri, komabe chifukwa cholephera kupirira mavuto alephera mayeso olowera ku koleji kawiri.
Minato amakumana ndi mtsikana wotchedwa Musubi, yemwe amagweradi kumwamba tsiku lina. Minato posakhalitsa amva kuti ndi "Sekirei" yemwe adamusankha ngati "Ashikabi", pakati pa gulu lachinsinsi la anthu omwe ali ndi chikhalidwe chobadwa nawo omwe amatha kupanga mgwirizano - mwa kupsompsonana - ndi a Sekirei. Izi zimawathandiza kugwiritsa ntchito mphamvu zawo zonse pothetsa mikangano ndi Sekirei wina ndipo amamumanga Sekirei kwa iye. Wopangidwa ndi atsikana okongola okwana 108, akazi a buxom, ndi bish? Nen, nkhondo ya Sekirei mu mpikisano wotchedwa "Sekirei Plan" wopangidwa ndi Hiroto Minaka, wapampando komanso woyambitsa wa MBI Corporation wodabwitsa komanso wamphamvu.
Minato posakhalitsa amva kuti kukhala mkazi wa mkazi sizosangalatsa komanso masewera, makamaka akasankhidwa ndi ena angapo a Sekirei aliyense akupanga mgwirizano naye, monga Ashikabi wawo. Tsopano, Minato apeze njira yothanirana ndi mikangano yomwe ikuwopseza moyo wa Sekirei Plan komanso kupikisana kwakukulu ndi mnzake.
Sekirei ndi zinthu zoyendetsedwa kwambiri pogwiritsa ntchito nambala ina ngati ya munthu. Sitima yapamtunda ya Sekirei idagwa Padziko Lapansi mu 1999 pachilumba cha Kamikura, ndipo adapezeka ndi ophunzira awiri, Hiroto Minaka (yemwe angakhale wapampando wa MBI) ndi Takami Sahashi (wofufuza wamkulu wa MBI komanso amayi a Minato). Atakwera, awiriwa adapeza mitundu 108 ya moyo, yofotokozedwa ngati "Mzati umodzi ndi mbalame zazing'ono 107".
